Transcriptional rewiring over evolutionary timescales changes quantitative and qualitative properties of gene expression
نویسندگان
چکیده
منابع مشابه
Transcriptional rewiring over evolutionary timescales changes quantitative and qualitative properties of gene expression
Evolutionary changes in transcription networks are an important source of diversity across species, yet the quantitative consequences of network evolution have rarely been studied. Here we consider the transcriptional 'rewiring' of the three GAL genes that encode the enzymes needed for cells to convert galactose to glucose. In Saccharomyces cerevisiae, the transcriptional regulator Gal4 binds a...
متن کاملVerifying qualitative and quantitative properties with LTL over concrete domains
We introduce different extensions of LTL where propositional variables are replaced by constraints interpreted in Z. We show different decidability and complexity results for the satisfiability and model checking problems of these logics. The extension of LTL over a wide set of qualitative constraints is shown to be pspace-complete. When introducing some quantitative constraints, we must consid...
متن کاملsome properties of fuzzy hilbert spaces and norm of operators
in this thesis, at first we investigate the bounded inverse theorem on fuzzy normed linear spaces and study the set of all compact operators on these spaces. then we introduce the notions of fuzzy boundedness and investigate a new norm operators and the relationship between continuity and boundedness. and, we show that the space of all fuzzy bounded operators is complete. finally, we define...
15 صفحه اولDeletion bias in avian introns over evolutionary timescales.
The role that introns play in the function and evolution of nuclear genomes is not fully understood. Recent models of intron evolution suggest that selection and drift may interact to maintain introns in multicellular organisms. In addition, deletion mutations are more likely to become fixed than insertion mutations. Examination of indel substitutions over macroevolutionary timescales in pigeon...
متن کاملQuantitative and qualitative changes of essential oil of Artemisia haussckenechtii in different phenological stages
Background & Aim: Artemisia species with common Persian name of Dermaneh are found all over Iran and are used for treatment in infectious diseases such as malaria, hepatitis and other diseases. Some Artemisia species are used in traditionally as tonic and anti-helmintic in north of Iran. Artemisia haussknechtii is used in dyspepsia and other gastroint...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: eLife
سال: 2016
ISSN: 2050-084X
DOI: 10.7554/elife.18981